Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator.The Neurotensin precursor is processed in the central nervous system and in the intestine to generate the 13 amino acid processed Neurotensin peptide. While the processed Neurotensin peptide functions asa neurotransmitter to modulate dopaminergic signaling pathways in the brain,it acts as a parahormone that may contribute to the growth of human colon cancers in the gut.