Adiponectin (AdipoQ), an adipocyte-derived hormone, is one of the most abundant adipokines in the blood circulation.Adiponectin modulates a number of metabolic processes, including improving INS sensitivity and anti-inflammatory activity. Adiponectin exerts its effects by activating a range of different signaling molecules via binding to two transmembrane AdipoQ receptors, AdipoR1 and AdipoR2.AdipoQ May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors.