EGF is a member of the epidermal growth factor superfamily.This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types.This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor.Defects in this gene are the cause of hypomagnesemia type 4.Dysregulation of this gene has been associated with the growth and progression of certain cancers.
