ABCB11 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. The major canalicular bile salt export pump in man.Catalyzes the secretion of conjugated bile salts across the canalicular membrane of hepatocytes in an ATP-dependent manner.Transports taurine-conjugated bile salts more rapidly than glycine-conjugated bile salts.
