MAP2K1 and MAP2K2 are protein kinases with dual specificity, belonging to the MAP kinase kinase family. MAP kinases, also known as extracellular signal regulated kinases (ERKs), serve as integration points for various biochemical signals. This protein kinase is located upstream of MAP kinase and stimulates the enzymatic activity of MAP kinase under a wide range of intracellular and extracellular signals. As a key component of the MAP kinase signaling pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcriptional regulation, and development.
