Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. Apolipoproteins are protein components of plasma lipoproteins. The apolipoprotein C gene family encodes four homologous proteins designated apoC-I to -IV, which specifically modulate the metabolism of triglyceride-rich lipoproteins. The human apoC-III gene maps to chromosome 11q23 and encodes a protein that may delay catabolism of triglyceride-rich particles by inhibiting lipoprotein lipase and hepatic lipase. APOC3 has 99 amino acids and T64,T94,S95 are glycosylated.An increase in apoC-III levels induces the development of hypertriglyceridemia.
