SMARCD3 is a member of the SWI/SNF family of proteins, is a member of the SMARCD family and contains one SWIB domain.whose members display helicase and ATPase activities,ATP-dependent chromatin remodeling complexes play an essential role in the regulation of nuclear processes such as transcription and DNA replication and repair. In mice, the silencing of the gene encoding SMARCD3 leads to defects in heart morphogenesis. SMARCD3/BAF60C is part of the lipoBAF complex that remodels the chromaitn structure to activate lipogenic genes, promoting lipogenesis in response to feeding and insulin.
