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The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs.  S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation.  S100 genes include at least 13 members which are located as a cluster on chromosome 1q21.  This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis.


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