TPSAB1 is also named as TPS1, TPS2, TPSB1. Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1.Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors.It is the major neutral protease present in mast cells and secreted upon the coupled activation-degranulation response of this cell type.