KLF3 can affect neural tube formation and organ development by regulating the expression of genes related to cell differentiation. It can also inhibit adipocyte differentiation by suppressing the expression of C/EBP α and FAS genes; Simultaneously promoting the activity of PPAR γ promoter. KLF3 is closely related to neuronal differentiation, participating in the process of neural tube formation, and can also regulate the development and maturation of B cells. KLF3 may be involved in obesity, diabetes and other metabolic diseases.
