GAP-43 (growth associated protein 43), B-50, PP46, calmodulin-binding protein P-57, neuromodulin, neuron growth-associated protein 43, protein F1 is a crucial component for regenerative response in the nervous system. Aberrant GAP43 expression can be seen in patients diagnosed with schizophrenia and Alzheimer's disease. GAP-43 is normally produced by neurons during developmental growth and axonal regeneration, but it is also expressed in specific regions of the normal adult nervous system.
