Lao A; Wu J; Li D, et al., Functionalized Metal–Organic Framework‐Modified Hydrogel That Breaks the Vicious Cycle of Inflammation and ROS for Repairing of Diabetic Bone Defects. Small 2023, 2206919.
Wang Y; Wei H; Li K, et al., Ros-responsive dextran-phenylboronic acid-silibinin nanoparticles for targeting delivery of BAPTA-AM to effectively eliminate calcium overload-mediated inflammatory cascades and mitochondrial apoptosis: Alleviating acute liver injury. Chemical Engineering Journal 2024, 480, 148283.
Huang J; Wang X; Li N, et al., YY1 Lactylation Aggravates Autoimmune Uveitis by Enhancing Microglial Functions via Inflammatory Genes. Adv Sci (Weinh) 2024, e2308031.
Yang B; Ye Z; Zhu X, et al., The redox activity of polychlorinated biphenyl quinone metabolite orchestrates its pro-atherosclerosis effect via CAV1 phosphorylation. J Hazard Mater 2023, 457, 131697.
Yin K; Wang D; Zhang Y, et al., Dose-effect of polystyrene microplastics on digestive toxicity in chickens (Gallus gallus): Multi-omics reveals critical role of gut-liver axis. J Adv Res 2022.
Yao Y; Xu T; Li X, et al., Selenoprotein S maintains intestinal homeostasis in ulcerative colitis by inhibiting necroptosis of colonic epithelial cells through modulation of macrophage polarization. Theranostics 2024, 14 (15), 5903-5925.
Miao Z; Wang W; Cao Q, et al., Role of Selenoprotein W in participating in the progression of non-alcoholic fatty liver disease. Redox Biol 2024, 71, 103114.
Gou Y; Weng Y; Chen Q, et al., Carboxymethyl chitosan prolongs adenovirus-mediated expression of IL-10 and ameliorates hepatic fibrosis in a mouse model. Bioengineering & Translational Medicine 2022, 7 (3), e10306.
Yu Q; Sun H; Zhang L, et al., A Zwitterionic Hydrogel with Anti-Oxidative and Anti-Inflammatory Properties for the Prevention of Peritoneal Adhesion by Inhibiting Mesothelial-Mesenchymal Transition. Adv Healthc Mater 2023, e2301696.
Shi X; Xu T; Li X, et al., ROS mediated pyroptosis-M1 polarization crosstalk participates in inflammation of chicken liver induced by bisphenol A and selenium deficiency. Environ Pollut 2023, 324, 121392.
Li S; Gu X; Zhang M, et al., Di (2-ethylhexyl) phthalate and polystyrene microplastics co-exposure caused oxidative stress to activate NF-kappaB/NLRP3 pathway aggravated pyroptosis and inflammation in mouse kidney. Sci Total Environ 2024, 926, 171817.
Zhang X; Li B; Huo S, et al., Hexafluoropropylene oxide trimer acid exposure triggers necroptosis and inflammation through the Wnt/beta-catenin/NF-kappaB axis in the liver. Sci Total Environ 2023, 905, 167033.
Xing C; Yang F; Lin Y, et al., Hexavalent Chromium Exposure Induces Intestinal Barrier Damage via Activation of the NF-κB Signaling Pathway and NLRP3 Inflammasome in Ducks. Frontiers in Immunology 2022, 3777.
Kulyar M F; Mo Q; Yao W, et al., Modulation of apoptosis and Inflammasome activation in chondrocytes: co-regulatory role of Chlorogenic acid. Cell Commun Signal 2024, 22 (1), 2.
Liu S; Fan M; Xu J X, et al., Exosomes derived from bone-marrow mesenchymal stem cells alleviate cognitive decline in AD-like mice by improving BDNF-related neuropathology. J Neuroinflammation 2022, 19 (1), 35.
Liu S; Gao Z; He W, et al., The gut microbiota metabolite glycochenodeoxycholate activates TFR-ACSL4-mediated ferroptosis to promote the development of environmental toxin-linked MAFLD. Free Radic Biol Med 2022, 193 (Pt 1), 213-226.
Zhao H; Li M; Liu L, et al., Cordyceps militaris polysaccharide alleviates diabetic symptoms by regulating gut microbiota against TLR4/NF-kappaB pathway. Int J Biol Macromol 2023, 230, 123241.
Wang W; Wang Y; Wang F, et al., Gastrodin regulates the TLR4/TRAF6/NF-kappaB pathway to reduce neuroinflammation and microglial activation in an AD model. Phytomedicine 2024, 128, 155518.
Sun M; Zhan H; Long X, et al., Dehydrocostus lactone alleviates irinotecan-induced intestinal mucositis by blocking TLR4/MD2 complex formation. Phytomedicine 2024, 128, 155371.
Gong H; Han D; Luo Z, et al., Xiangshao Decoction alleviates gastric mucosal injury through NRF2 signaling pathway and reduces neuroinflammation in gastric ulcer rats. Phytomedicine 2023, 118, 154954.
Peng Y; Zhu J; Li Y, et al., Almond polysaccharides inhibit DSS-induced inflammatory response in ulcerative colitis mice through NF-kappaB pathway. Int J Biol Macromol 2024, 281 (Pt 1), 136206.
Liu J; Huang J; Gong B, et al., Polydatin protects against calcium oxalate crystal-induced renal injury through the cytoplasmic/mitochondrial reactive oxygen species-NLRP3 inflammasome pathway. Biomed Pharmacother 2023, 167, 115621.
Liu C; Guo X; Chen Y, et al., Anti-photoaging effect and mechanism of flexible liposomes co-loaded with apigenin and doxycycline. Biomed Pharmacother 2023, 164, 114998.
Hong T; Pan X; Xu H, et al., Jatrorrhizine inhibits Piezo1 activation and reduces vascular inflammation in endothelial cells. Biomed Pharmacother 2023, 163, 114755.
Fan M; Liu S; Sun H M, et al., Bilateral intracerebroventricular injection of streptozotocin induces AD-like behavioral impairments and neuropathological features in mice: Involved with the fundamental role of neuroinflammation. Biomed Pharmacother 2022, 153, 113375.
Li J; Wang X; Bai J, et al., Fucoidan modulates SIRT1 and NLRP3 to alleviate hypertensive retinopathy: in vivo and in vitro insights. J Transl Med 2024, 22 (1), 155.
Huo Q; Shi Y; Qi Y, et al., Biomimetic silibinin-loaded macrophage-derived exosomes induce dual inhibition of Abeta aggregation and astrocyte activation to alleviate cognitive impairment in a model of Alzheimer's disease. Mater Sci Eng C Mater Biol Appl 2021,129, 112365.
Jing F; Zou Q; Wang Y, et al., Activation of microglial GLP-1R in the trigeminal nucleus caudalis suppresses central sensitization of chronic migraine after recurrent nitroglycerin stimulation. J Headache Pain 2021, 22 (1), 86.
Geng X; Liu K; Wang J, et al., Preparation of Ultra-Small Copper Nanoparticles-Loaded Self-Healing Hydrogels with Antibacterial, Inflammation-Suppressing and Angiogenesis-Enhancing Properties for Promoting Diabetic Wound Healing. Int J Nanomedicine 2023, 18, 3339-3358.
Ren S; Wang J; Dong Z, et al., Perfluorooctane sulfonate induces ferroptosis-dependent non-alcoholic steatohepatitis via autophagy-MCU-caused mitochondrial calcium overload and MCU-ACSL4 interaction. Ecotoxicol Environ Saf 2024, 280, 116553.
Wang J; Yin Y; Zhang Q, et al., HgCl(2) exposure mediates pyroptosis of HD11 cells and promotes M1 polarization and the release of inflammatory factors through ROS/Nrf2/NLRP3. Ecotoxicol Environ Saf 2023, 269, 115779.
Huo S; Zhang X; Xu J, et al., Parkin-mediated mitophagy protects against aluminum trichloride-induced hippocampal apoptosis in mice via the mtROS-NLRP3 pathway. Ecotoxicol Environ Saf 2023, 264, 115459.
Ba T; Zhao D; Chen Y, et al., L-Citrulline Supplementation Restrains Ferritinophagy-Mediated Ferroptosis to Alleviate Iron Overload-Induced Thymus Oxidative Damage and Immune Dysfunction. Nutrients 2022, 14 (21), 4549.
Wang Y M; Chu T J; Wan R T, et al., Quercetin ameliorates atherosclerosis by inhibiting inflammation of vascular endothelial cells via Piezo1 channels. Phytomedicine 2024, 132, 155865.
Wang S W; Lan T; Zheng F, et al., Celastrol inhibits TXNIP expression to protect pancreatic beta cells in diabetic mice. Phytomedicine 2022, 104, 154316.
Zhou L M; Fan J H; Xu M M, et al., Epiberberine regulates lipid synthesis through SHP (NR0B2) to improve non-alcoholic steatohepatitis. Biochim Biophys Acta Mol Basis Dis 2023, 166639.
Liu L; Yang Y; Fang R, et al., Giardia duodenalis and Its Secreted PPIB Trigger Inflammasome Activation and Pyroptosis in Macrophages through TLR4-Induced ROS Signaling and A20-Mediated NLRP3 Deubiquitination. Cells 2021, 10 (12).
Liu T; Zhang W; Zeng W, et al., Downregulation of OPN3 Gene Induces Ferroptosis, Apoptosis, and Pyroptosis of Human Dermal Fibroblasts In Vitro. J Invest Dermatol 2024, 144 (10), 2305-2308 e6.
Luo K; Li X; Wang L, et al., Ascorbic Acid Regulates the Immunity, Anti-Oxidation and Apoptosis in Abalone Haliotis discus hannai Ino. Antioxidants (Basel) 2021, 10 (9).
Che H Y; Zhou C H; Lyu C C, et al., Allicin Alleviated LPS-Induced Mastitis via the TLR4/NF-kappaB Signaling Pathway in Bovine Mammary Epithelial Cells. Int J Mol Sci 2023, 24 (4).
Ren S; Liang P; Feng R, et al., The phosphorylation of Smad3 by CaMKIIgamma leads to the hepatocyte pyroptosis under perfluorooctane sulfonate exposure. Ecotoxicol Environ Saf 2024, 284, 116924.
Zhang Q; Li S; Fang J, et al., The combined effects of polystyrene of different sizes and cadmium in mouse kidney tissues. Ecotoxicol Environ Saf 2024, 281, 116660.
Cai J; Yang J; Chen X, et al., Melatonin ameliorates trimethyltin chloride-induced cardiotoxicity: The role of nuclear xenobiotic metabolism and Keap1-Nrf2/ARE axis-mediated pyroptosis. Biofactors 2021.
Zou Y Y; Tang X B; Chen Z L, et al., Exercise intervention improves mitochondrial quality in non-alcoholic fatty liver disease zebrafish. Front Endocrinol (Lausanne) 2023, 14, 1162485.
Wang Q; Jia F; Guo C, et al., PINK1/Parkin-mediated mitophagy as a protective mechanism against AFB1-induced liver injury in mice. Food Chem Toxicol 2022, 164, 113043.
Zhu Y; Zhang J; Yao X, et al., Ubiquitinated gasdermin D mediates arsenic-induced pyroptosis and hepatic insulin resistance in rat liver. Food Chem Toxicol 2021, 160, 112771.
Liu T; Shu J; Liu Y, et al., Atorvastatin attenuates ferroptosis-dependent myocardial injury and inflammation following coronary microembolization via the Hif1a/Ptgs2 pathway. Front Pharmacol 2022, 13, 1057583.
Du T; Yan Z; Zhu S, et al., QKI deficiency leads to osteoporosis by promoting RANKL-induced osteoclastogenesis and disrupting bone metabolism. Cell Death Dis 2020, 11 (5), 330.
Yu Y; Fan Z; Han Y, et al., miR-135 protects against atrial fibrillation by suppressing intracellular calcium-mediated NLRP3 inflammasome activation. J Cell Commun Signal 2023.
Liu J; Zhang W; Li X, et al., New Insights into Baicalein's Effect on Chlorpyrifos-Induced Liver Injury in Carp: Involving Macrophage Polarization and Pyropto sis. J Agric Food Chem 2023, 71 (9), 4132-4143.
Liao C; Wang D; Qin S, et al., Inflammatory-Dependent Bidirectional Effect of Bile Acids on NLRP3 Inflammasome and Its Role in Ameliorating CPT-11-Induced Colitis. Front Pharmacol 2022, 13, 677738.
Sun H-l; Bian H-g; Liu X-m, et al., GRP/GRPR signaling pathway aggravates hyperuricemia-induced renal inflammation and fibrosis via ABCG2-dependent mechanisms. Biochemical Pharmacology 2023, 218, 115901.
Fan J; Ren M; Chen W, et al., Celastrol relieves myocardial infarction-induced cardiac fibrosis by inhibiting NLRP3 inflammasomes in rats. Int Immunopharmacol 2023, 121, 110511.
Wang F; Song Y; Liu P, et al., Rapamycin suppresses neuroinflammation and protects retinal ganglion cell loss after optic nerve crush. Int Immunopharmacol 2023, 119, 110171.
Zhang X; Zhang H; Gao Y, et al., Forsythoside A regulates autophagy and apoptosis through the AMPK/mTOR/ULK1 pathway and alleviates inflammatory damage in MAC-T cells. Int Immunopharmacol 2023, 118, 110053.
Wang N; Ma Y; Liu Z, et al., Hydroxytyrosol prevents PM2.5-induced adiposity and insulin resistance by restraining oxidative stress related NF-kappaB pathway and modulation of gut microbiota in a murine model. Free Radic Biol Med 2019, 141, 393-407.
Yang X; Tian Y; Liu J, et al., Peony Pollen Protects against Primary Dysmenorrhea in Mice by Inhibiting Inflammatory Response and Regulating the COX2/PGE2 Pathway. Int J Mol Sci 2023, 24 (24).
Liu S; Liu J; Wu Y, et al., Genistein upregulates AHR to protect against environmental toxin-induced NASH by inhibiting NLRP3 inflammasome activation and reconstructing antioxidant defense mechanisms. J Nutr Biochem 2023, 109436.
Ma W; Liu Y; Xu L, et al., The role of selenoprotein M in nickel-induced pyroptosis in mice spleen tissue via oxidative stress. Environ Sci Pollut Res Int 2022.
Yin K; Lu H; Zhang Y, et al., Secondary brain injury after polystyrene microplastic-induced intracerebral hemorrhage is associated with inflammation and pyroptosis. Chem Biol Interact 2022, 110180.
Hu X; Chi Q; Liu Q, et al., Atmospheric H2S triggers immune damage by activating the TLR-7/MyD88/NF-kappaB pathway and NLRP3 inflammasome in broiler thymus. Chemosphere 2019, 237, 124427.
Liao K; Lv D Y; Yu H L, et al., iNOS regulates activation of the NLRP3 inflammasome through the sGC/cGMP/PKG/TACE/TNF-alpha axis in response to cigarette smoke resulting in aortic endothelial pyroptosis and vascular dysfunction. Int Immunopharmacol 2021, 101 (Pt B), 108334.
Li L; Cheng D; An X, et al., Mesenchymal stem cells transplantation attenuates hyperuricemic nephropathy in rats. Int Immunopharmacol 2021, 99, 108000.
Wang P; Yang C; Lu J, et al., Sirt1 protects against intervertebral disc degeneration induced by 1,25-dihydroxyvitamin D insufficiency in mice by inhibiting the NF-kappaB inflammatory pathway. J Orthop Translat 2023, 40, 13-26.
Zhang Z; Chen H; Li Q, High-fat diet led to testicular inflammation and ferroptosis via dysbiosis of gut microbes. Int Immunopharmacol 2024, 142 (Pt B), 113235.
Yang Y; He Y; Yi G, et al., Excretory/secretory antigens from Trichinella spiralis muscle larvae ameliorate HFD-induced non-alcoholic steatohepatitis via driving macrophage anti-inflammatory activity. Int Immunopharmacol 2024, 142 (Pt A), 113103.
Chi Q; Xia Y; Luo D, et al., In vitro and in silico analyses reveal the toxicity of metolachlor to grass carp hepatocytes and the antagonism of melatonin. Pestic Biochem Physiol 2024, 202, 105930.
Ma D C; Zhang N N; Zhang Y N, et al., Kv1.3 channel blockade alleviates cerebral ischemia/reperfusion injury by reshaping M1/M2 phenotypes and compromising the activation of NLRP3 inflammasome in microglia. Exp Neurol 2020, 332, 113399.
Huang L; Li Y; Cheng Z, et al., PCSK9 Promotes Endothelial Dysfunction During Sepsis Via the TLR4/MyD88/NF-kappaB and NLRP3 Pathways. Inflammation 2022.
Su X; Li Q; Yang M, et al., Resveratrol protects against a high-fat diet-induced neuroinflammation by suppressing mitochondrial fission via targeting SIRT1/PGC-1alpha. Exp Neurol 2024, 380, 114899.
Wu Y; Zhou J; Zuo X, et al., Yanggan Jiangmei Formula alleviates hepatic inflammation and lipid accumulation in non-alcoholic steatohepatitis by inhibiting the NF-kappaB/NLRP3 signaling pathway. Chin J Nat Med 2024, 22 (3), 224-234.
Meng X; Yin K; Zhang Y, et al., Polystyrene microplastics induced oxidative stress, inflammation and necroptosis via NF-kappaB and RIP1/RIP3/MLKL pathway in chicken kidney. Toxicology 2022, 478, 153296.
Zhang Y; Liu Q; Yin H, et al., Cadmium exposure induces pyroptosis of lymphocytes in carp pronephros and spleens by activating NLRP3. Ecotoxicol Environ Saf 2020, 202, 110903.
Wang N; Liu Y; Ma Y, et al., Hydroxytyrosol ameliorates insulin resistance by modulating endoplasmic reticulum stress and prevents hepatic steatosis in diet-induced obesity mice. J Nutr Biochem 2018, 57, 180-188.
Wu H R; Zhang C N; Dou B Q, et al., Identification of O-arylated huperzinines as novel cholinergic anti-inflammatory pathway agonists against gout arthritis. Bioorg Chem 2024, 152, 107716.
Zhu L-H; Xu Y-Y; Zhu L-p, et al., Protective effects of Cyclocarya paliurus on hyperuricemia and urate-induced inflammation. Journal of Functional Foods 2022, 94, 105130.
Xu F; Ji Q; Zhang J, et al., AlCl3 inhibits LPS-induced NLRP3 inflammasome activation and IL-1beta production through suppressing NF-kappaB signaling pathway in murine peritoneal macrophages. Chemosphere 2018, 209, 972-980.
Wang W T; Feng F; Zhang M M, et al., Red nucleus mGluR2 but not mGluR3 mediates inhibitory effect in the development of SNI-induced neuropathological pain by suppressing the expressions of TNF-alpha and IL-1beta. Neurochem Int 2024, 179, 105840.
Ni X; Hong H; Xu H, et al., Exposure to Trimethyltin Chloride Induces Pyroptosis and Immune Dysfunction in Grass Carp CIK Cells by Activating the NF-kappaB Pathway Through Oxidative Stress. Environ Toxicol 2024.
Bi Y; Wei H; Chai Y, et al., Intermittent mild cold acclimation ameliorates intestinal inflammation and immune dysfunction in acute cold-stressed broilers by regulating the TLR4/MyD88/NF-kappaB pathway. Poult Sci 2024, 103 (5), 103637.
Zhang Y; Li G; Zhao Y, et al., Inhibition of calcium imbalance protects hepatocytes from vanadium exposure-induced inflammation by mediating mitochondrial-associated endoplasmic reticulum membranes in ducks. Poult Sci 2023, 102 (12), 103013.
Jiang Y; Geng Y; Gao R, et al., Maternal exposure to ZIF-8 derails placental function by inducing trophoblast pyroptosis through neutrophils activation in mice. Food Chem Toxicol 2024, 187, 114604.
Lu D; Liu Y; Mai H, et al., Rosuvastatin Reduces Neuroinflammation in the Hemorrhagic Transformation After rt-PA Treatment in a Mouse Model of Experimental Stroke. Front Cell Neurosci 2018, 12, 225.
Yuan W; Qiu T; Yao X, et al., Hsp47 acts as a bridge between NLRP3 inflammasome and hepatic stellate cells activation in arsenic-induced liver fibrosis. Toxicol Lett 2022.
Liang H; Cheng R; Wang J, et al., Mogrol, an aglycone of mogrosides, attenuates ulcerative colitis by promoting AMPK activation. Phytomedicine 2021, 81, 153427.
Jiang L; Qiu T; Yao X, et al., MEHP induces pyroptosis and autophagy alternation by cathepsin B activation in INS-1 cells. Environ Sci Pollut Res Int 2021.
Tian X; Wang W T; Zhang M M, et al., Red nucleus mGluR1 and mGluR5 facilitate the development of neuropathic pain through stimulating the expressions of TNF-alpha and IL-1beta. Neurochem Int 2024, 178, 105786.
Jing H; Wang F; Gao X J, Lithium intoxication induced pyroptosis via ROS/NF-kappaB/NLRP3 inflammasome regulatory networks in kidney of mice. Environ Toxicol 2022.
Liu Y; Ma W; Liu Q, et al., Decreased thioredoxin reductase 3 expression promotes nickel-induced damage to cardiac tissue via activating oxidative stress-induced apoptosis and inflammation. Environ Toxicol 2022.
Jing H; Yan N; Fan R, et al., Arsenic Activates the NLRP3 Inflammasome and Disturbs the Th1/Th2/Th17/Treg Balance in the Hippocampus in Mice. Biol Trace Elem Res 2023, 201 (7), 3395-3403.
Liu Z; Wang N; Ma Y, et al., Hydroxytyrosol Improves Obesity and Insulin Resistance by Modulating Gut Microbiota in High-Fat Diet-Induced Obese Mice. Front Microbiol 2019, 10, 390.
Pei P; Yao X; Jiang L, et al., Inorganic arsenic induces pyroptosis and pancreatic beta cells dysfunction through stimulating the IRE1alpha/TNF-alpha pathway and protective effect of taurine. Food Chem Toxicol 2019, 125, 392-402.
Qi C; Zhou J; Wang Z, et al., Cigarette smoke extract combined with lipopolysaccharide reduces OCTN1/2 expression in human alveolar epithelial cells in vitro and rat lung in vivo under inflammatory conditions. Int Immunopharmacol 2020, 87, 106812.
Cao Z; Yang F; Lin Y, et al., Selenium Antagonizes Cadmium-Induced Inflammation and Oxidative Stress via Suppressing the Interplay between NLRP3 Inflammasome and HMGB1/NF-κB Pathway in Duck Hepatocytes. International Journal of Molecular Sciences 2022, 23 (11), 6252.
Ma D C; Zhang N N; Zhang Y N, et al., Salvianolic Acids for Injection alleviates cerebral ischemia/reperfusion injury by switching M1/M2 phenotypes and inhibiting NLRP3 inflammasome/pyroptosis axis in microglia in vivo and in vitro. J Ethnopharmacol 2021, 270, 113776.
Li X; Lu H Y; Jiang X W, et al., Cinnamomum cassia extract promotes thermogenesis during exposure to cold via activation of brown adipose tissue. J Ethnopharmacol 2021, 266, 113413.
Ye Y; Zhang Y; Wang B, et al., CXCR1/CXCR2 antagonist G31P inhibits nephritis in a mouse model of uric acid nephropathy. Biomed Pharmacother 2018, 107, 1142-1150.
Li C; Zhao Z; Jin J, et al., NLRP3-GSDMD-dependent IL-1beta Secretion from Microglia Mediates Learning and Memory Impairment in a Chronic Intermittent Hypoxia-induced Mouse Model. Neuroscience 2024, 539, 51-65.
Liu L; Wang N; Ma Y, et al., Saponins from Boussingaultia gracilis prevent obesity and related metabolic impairments in diet-induced obese mice. Food Funct 2018, 9 (11), 5660-5673.
Chen T; Li Y; Ni W, et al., Human Neural Stem Cell-Conditioned Medium Inhibits Inflammation in Macrophages Via Sirt-1 Signaling Pathway In Vitro and Promotes Sciatic Nerve Injury Recovery in Rats. Stem Cells Dev 2020, 29 (16), 1084-1095.
